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Mechanism of Action of Tirzepatide Tirzepatide mimics the action of natural human hormones to enhance insulin secretion, inhibit glucagon release, delay gastric emptying, and suppress appetite, thereby achieving blood glucose lowering and weight reduction effects

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Melatonin synthesis was evaluated by measuring urinary 6-sulfatoxymelatonin, the primary metabolite of melatonin, which increased 1.6-fold in the Epitalon group relative to placebo

Delayed Treatment: Vitamin B12 deficiency left untreated for longer than 3 months may cause permanent spinal cord and nerve damage

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